Before breaking point, there's CareLoop Health
At CareLoop Health, we're transforming care for people living with severe mental illnesses through our breakthrough platform that integrates P4 medicine: Predictive, Preventative, Personalised, and Participatory.
Our vision
Our vision
We envision a world where predictive, personalised care keeps people with severe mental illness well at home and connected to their communities, preventing escalation and eliminating crisis.
Our mission
Our mission
We're on a mission to transform mental healthcare using intelligent software to predict problems, prevent escalation, and personalise care to individual needs while supporting patient participation.
As healthcare systems struggle to meet increasing demand, both human and financial costs rise. Our approach shifts care from reactive to proactive, helping more people stay well in their communities.
The challenge
The challenge
5% of the global population has a severe mental health problem, with many experiencing crisis episodes requiring acute care. For those with psychosis:
- Only 20% achieve full recovery
- The remaining 80% face a 25% annual relapse risk
- Early warning signs appear just 3-10 days before relapse
- Traditional care models often schedule appointments 12 weeks apart
This gap leads to preventable crises with devastating human costs — reduced life expectancy, 93% unemployment rate — and financial burden, consuming 4% of the NHS budget in the UK and $62 billion annually in the US.
Our approach
CareLoop integrates P4 medicine to enhance outcomes for people with severe mental illness:
- Predictive: Our AI-powered system detects early warning signs before relapse.
- Preventative: We identify subtle changes to reduce hospital admissions.
- Personalised: Each care pathway is tailored to individual needs.
- Participatory: We empower patients to actively engage in their care.
Our platform has been co-designed at every stage by the people who matter most:
- Individuals: Bringing lived experience and practical insights
- Clinicians: Ensuring alignment with clinical best practices
- Researchers: Providing evidence-based methodologies
- Software Engineers: Creating intuitive, effective technology
As a spinout of the University of Manchester, we maintain strong links with our academic heritage and are proud of our relationships within the NHS in the UK. This foundation gives us the credibility and expertise to deliver solutions that make a real difference.
As a business and as individuals, we recognise our responsibility to protect the planet for future generations. To achieve Net Zero carbon emissions by 2045, we are mindful of how we work and who we partner with.
The team
Zoë Blake
Chief Executive Officer & Co-Founder
Zoë is our Chief Executive Officer, before joining CareLoop Health she served as CEO of the digital mental health platform Kooth (previously XenZone). Zoë is a seasoned business leader with over 25 years leading dynamic teams operating in fast changing, innovation lead organisations.
Zoë Blake
Chief Executive Officer & Co-Founder
Pauline Wheelan
Chief Operating Officer & Co-Founder
In her 20+ years working in software engineering, Pauline has led high performing teams in consultancies, large corporates, and academia. Over the last decade, Pauline has built and implemented digital solutions targeted at both physical and mental health, many of which are deployed in the NHS. She is a Digital Health Lead at the University of Manchester, and the Digital Director of GM.Digital at Greater Manchester Mental Health NHS Foundation trust.
Pauline Wheelan
Chief Operating Officer & Co-Founder
Professor Sandra Bucci
Co-Founder
Professor Bucci is the first ever NIHR Research Professor in Digital Mental Health in the UK, Professor of Clinical Psychology at The University of Manchester, and Honorary Consultant Clinical Psychologist at Greater Manchester Mental Health NHS Foundation Trust (GMMH). With over 20 years clinical experience working with people with complex mental health needs, Sandra is also co-Director of the Complex Trauma and Resilience Research Unit in GMMH.
Professor Sandra Bucci
Co-Founder
Professor Shôn Lewis
Chief Medical Officer & Co-Founder
A psychiatrist for over 30 years, Shôn’s keen interest in the use of digital technology within mental health was the genesis of CareLoop Health. He trained at the Maudsley Hospital and has worked within the NHS throughout his career. His many accolades include the platinum clinical excellence award for contribution to the NHS.
Professor Shôn Lewis
Chief Medical Officer & Co-Founder
Professor John Ainsworth
Director & Co-Founder
John is Chief Product Officer at CareLoop Health. A software engineering veteran with a career spanning commercial R&D and academia. John is Professor of Health Informatics at the University of Manchester and was the Director of the Centre for Health Informatics. Since 2009 he has undertaken pioneering research into the use of smartphones in mental health for connected care.
Professor John Ainsworth
Director & Co-Founder
